首页工具

登录

搜索结果

Search Results for " ifn γ "

Targets Recommended: P450 STAT

53

抑制剂 & 化合物

11

天然产物

49

重组蛋白

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name	Target	Signaling Pathways
T9043	AS1810722	P450; STAT	JAK/STAT signaling; Metabolism; Stem Cells
	AS1810722 是口服有效的STAT6抑制剂，IC50为 1.9 nM。它是一种稠合双环嘧啶衍生物，对有良好的CYP3A4抑制作用，具有用于过敏性疾病，如哮喘和特应性疾病的研究潜力。
T21694	(R)-Lisofylline (R)-Lisophylline	STAT	JAK/STAT signaling; Stem Cells
	(R)-Lisofylline ((R)-Lisophylline) 是溶血磷脂酸酰基转移酶的抑制剂 (IC50 = 0.6 µM)。 (R)-Lisofylline 可中断 IL-12 信号介导的 STAT4 激活，可用于治疗 1 型糖尿病和自身免疫性疾病的研究。
T8692	(Rac)-Benpyrine	TNF	Apoptosis
	(Rac)-Benpyrine 是一种有效且具有口服活性的 TNF-α 抑制剂，是Benpyrine 的外消旋体。它可研究TNF-α介导的炎症和自身免疫性疾病。
T9616	PD-1/PD-L1-IN-10	PD-1/PD-L1	Apoptosis; Cell Cycle/Checkpoint; Immunology/Inflammation
	PD-1/PD-L1-IN-10 是一种口服有效的PD-1/PD-L1抑制剂 (IC50of 2.7 nM)，显示出抗肿瘤活性。
T1781	GW9508 GW 9508	GPR; Potassium Channel	Endocrinology/Hormones; GPCR/G Protein; Membrane transporter/Ion channel
	GW 9508 是一种选择性 G 蛋白偶联受体FFA1(GPR40) 和GPR120激动剂。它是一种葡萄糖敏感性胰岛素促分泌剂和 ATP 敏感性钾通道开放剂，具有抗炎和抗动脉粥样硬化活性。
T76637	IFN-γ Antagonist 1
	IFN-γAntagonist 1 (AYCRDGKIGPPKLDIRKEEKQI)，一种干扰素γ (IFN-γ) 拮抗剂，通过抑制IC50约为35 μM的IFN-γ诱导的HLR/DR抗原在Colo 205细胞上的表达展现作用。该化合物在免疫调节领域具有潜在应用。
T83628	TNF/IFNγ-IN-1	Antioxidant; TNF; COX	Apoptosis; Immunology/Inflammation; Neuroscience; oxidation-reduction
	TNF/IFNγ-IN-1(TGA) 是 TNF 和 IFN-γ 的双重抑制剂。TNF/IFNγ-IN-1 具有潜在的抗氧化和抗炎活性，可用于类似阿尔茨海默等的神经退行性疾病。
T76638	IFN-γ Antagonist 1 acetate
	IFN-γAntagonist 1 (AYCRDGKIGPPKLDIRKEEKQI) acetate 作为一种干扰素 γ (IFN-γ) 拮抗剂，能够在 Colo 205 细胞中抑制 IFN-γ诱导的 HLR/DR 抗原表达，其 IC50 值约为 35 μM，显示出在免疫调节中的潜在应用价值。
T11630	IFN alpha-IFNAR-IN-1 hydrochloride	Others; IFNAR	Immunology/Inflammation; Others
	IFN alpha-IFNAR-IN-1 hydrochloride 是 IFN-α 和 IFNAR 相互作用的抑制剂。 IFN alpha-IFNAR-IN-1 hydrochloride 抑制 BM-pDCs 的 MVA 诱导的 IFN-α 反应，IC50 为 2-8 μM。
T38158	StA-IFN-1
	StA-IFN-1 is an inhibitor of the interferon (IFN) induction pathway with an IC50 value of 4.1 μM in a GFP reporter assay for IFN induction similar to TPCA-1 , which specifically inhibits the IKKβ component of the IFN induction pathway. It does not show inhibitory activity in a GFP reporter assay for IFN signaling in which ruxolitinib , which is specific for the IFN signaling component JAK1, is active. StA-IFN-1 reduces the levels of IFN-β, but not ISG MxA, mRNA, suggesting that it is selective f...
T78262	Anti-Mouse IFN gamma Antibody (H22)	IFNAR	Immunology/Inflammation
	Anti-Mouse IFN gamma Antibody为针对小鼠IFN gamma的IgG类免疫抑制性抗体，其宿主为Armenian Hamster。
T76742	Emapalumab NI-0501	COX	Immunology/Inflammation; Neuroscience
	Emapalumab (NI-0501) 是一种人源化针对干扰素 γ 的人单克隆抗体的 IgG1 单克隆抗体，可阻断其与细胞表面受体的结合并激活炎症信号。Emapalumab 与游离的 IFN-γ 以及与其受体结合的 IFN-γ 具有高结合力 (Kd=1.4 pM)。Emapalumab 可用于噬血细胞性淋巴组织细胞增多症 (HLH) 的研究。
T16169	N-alpha-Tosyl-L-lysine chloromethyl ketone hydrochloride N-alpha-Tosyl-L-lysine_chloromethyl_ketone_hydrochloride	Others; Proteasome; COX	Immunology/Inflammation; Neuroscience; Others; Proteases/Proteasome; Ubiquitination
	N-alpha-Tosyl-L-lysine chloromethyl ketone hydrochloride (N-alpha-Tosyl-L-lysine_chloromethyl_ketone_hydrochloride) 是胰蛋白酶样蛋白酶的抑制剂。 N-alpha-Tosyl-L-lysine chloromethyl ketone hydrochloride 对 IFN-γ 活性具有抑制作用。
T4403	AX-024 hydrochloride AX-024 HCl	IL Receptor; TNF; COX; IFNAR; Interleukin	Apoptosis; Immunology/Inflammation; Neuroscience
	AX-024 hydrochloride (AX-024 HCl) 是一种细胞因子释放抑制剂，可强烈抑制 IL-6、TNFα、IFN-γ、IL-10 和 IL-17A 的产生。它是口服可利用的 TCR-Nck 相互作用抑制剂，可选择性地抑制 TCR 触发的 T 细胞活化。它通过靶向 SH3结构域调节细胞信号传导，具有低毒、高效和高选择性的特点。
T76691	Monalizumab	IFNAR; Chk	Cell Cycle/Checkpoint; Immunology/Inflammation
	Monalizumab 是一种新型靶向自然杀伤细胞群 2A (NKG2A) 的免疫检查点抑制剂。Monalizumab 是一种人源化抗 NKG2A 的单克隆抗体，可促使 IFN-γ 产生，从而激活自然杀伤细胞功能。Monalizumab 具有抗肿瘤活性，可用于研究颈部鳞状细胞癌 (HNSCC)。
T2168	2-(1,8-naphthyridin-2-yl)phenol	STAT	JAK/STAT signaling; Stem Cells
	2-NP 是选择性的STAT1转录增强剂。它能够增强 IFN-γ 的功能，提高对人乳腺癌和纤维肉瘤细胞增殖的抑制能力。
T13063	T6167923	MyD88	Immunology/Inflammation
	T6167923是一种有效的、选择性的MyD88依赖性信号通路抑制剂。T6167923 与 MyD88 的 Toll/IL1 受体 (TIR) 结构域结合良好，破坏 MyD88 的同二聚体形成。T6167923 抑制 NF-κB 驱动的葡萄球菌肠毒素AP (SEAP) 活性，并且改善抗炎活性，对 IFN-γ，IL-1β，IL-6 和 TNF-α 的 IC50分别为 2.7 μM，2.9 μM，2.66 μM 和 2.66 μM。
T36169	15-LOX-1 inhibitor 1
	9c(i472) is an inhibitor of 15-lipoxygenase-1 (15-LO-1; IC50 = 0.19 μM).1 It decreases LPS- and IFN-γ-induced NF- B activity in RAW-Blue cells when used at concentrations of 0.2, 1, and 5 μM. 9c(i472) reduces LPS- and IFN-γ-induced increases in Nos2 expression and lipid peroxidation in RAW 264.7 cells when used at a concentration of 5 μM.
T64280	ODN 2216
	ODN 2216 是一种 TLR9 (toll-like receptor 9) 配体或激动剂，能够诱导产生大量的 IFN-α 和 IFN-β。ODN 2216 可以利用 pDC (浆细胞样 DC) 诱导 IFN-α，以及利用 DC (树突状细胞) 产生IL-12 (p40)。ODN 2216 能够间接的、在 IFN-α/β 介导下刺激外周血单核细胞 (PBMC) 产生 IFN-γ。ODN 2216 可以激活 NK 细胞，诱导 IFN-γ 产生 TCR 触发的 CD4+T 细胞。
T79189	1-Isopropyltryptophan 1-IsoPT	Indoleamine 2,3-Dioxygenase (IDO)	Metabolism
	1-Isopropyltryptophan (1-IsoPT)为IDO1抑制剂，能够抑制IFN-γ刺激下IDO-1与IDO-2 mRNA的表达水平。
T16570	Pralnacasan VX-740,HMR 3480	Others	Others
	Pralnacasan inhibits proinflammatory cytokines IL-18, IL-1β , and IFN-γ. Pralnacasan is an effective, non-peptide, and orally active interleukin-1β converting enzyme inhibitor (Ki: 1.4 nM). Pralnacasan has the potential for osteoarthritis and rheumatoid a
T71839	ATV399
	ATV399 is an inhibitor of iNOS dimerization which protects against Cytokine-Induced rat β-cell dysfunction, thereby inhibiting cleaved caspase-9 activation and subsequent β-cell apoptosis induced by a combination of IL-1β, IFN-γ, and high glucose.
T81840	MBP (83-99)
	MBP (83-99)为MBP特异性的T细胞认可的主要免疫表位，能够诱导T细胞增殖并促使IFN-γ释放。
T82743	CFP10 (71–85)
	CFP10 (71–85) 是具生物活性的肽类，能激活表达不同MHC II类与I类分子的人类CD4+和CD8+ T细胞，诱导IFN-γ产生及CTL活性。(CFP10 71–85).
T26895	BRD0476 BRD-0476,ML 187,ML187,ML-187,BRD 0476
	BRD0476 is a suppressor of pancreatic β-cell apoptosis. BRD0476 inhibits interferon-gamma (IFN-γ)-induced Janus kinase 2 (JAK2) and signal transducer and activation of transcription 1 (STAT1) signaling to promote β-cell survival. BRD0476 inhibits JAK-STAT
T62726	Phenylpyropene C
	Phenylpyropene C (S14-95) 是一种 JAK/STAT 通路抑制剂，对 IFN-γ 介导的报告基因表达表现出抑制作用 (IC50:5.4~10.8 μM)。Phenylpyropene C 也是一种酰基辅酶 A 的抑制剂 (IC50: 16.0 μM)。
T22506	3,4-DAA	NOS	Immunology/Inflammation
	3,4-DAA 具有抗炎活性，可改善急性肝同种异体移植损伤，通过抑制肠道屏障功能障碍和 NF-κB 活化来缓解严重的急性胰腺炎。3,4-DAA 抑制由 IFN-γ 和脂多糖诱导的 EOC20 细胞诱导型一氧化氮合酶 (iNOS) 发挥作用。
T60266	(Rac)-Indoximod
	(Rac)-Indoximod (1-Methyl-DL-tryptophan) is a potent inhibitor of indoleamine 2,3-dioxygenase (IDO). Combined treatment with IFN-γ and (Rac)-Indoximod significantly suppresses the activity of α-SMA-expressing human cardiac myofibroblasts (hCMs) and promotes apoptosis by up-regulating the genes IRF-1, Fas, and FasL. Moreover, this co-treatment effectively improves cardiac fibrosis[1].
T78755	PD-1/PD-L1-IN-31	PD-1/PD-L1	Apoptosis; Cell Cycle/Checkpoint; Immunology/Inflammation
	PD-1/PD-L1-IN-31为具高效PD-1/PD-L1抑制能力的化合物（IC50=2.2 nM），能激进IFN-γ分泌及激活外周血单核细胞（PBMC），进而抑制肿瘤细胞生长。
T72017	6(5H)-Phenanthridinone
	6(5H)-Phenanthridinone is an inhibitor of poly(ADP-ribose) polymerase 1 (PARP1) and PARP2. It decreases radiation-induced PARP activity and proliferation of RDM4 murine lymphoma cells. 6(5H)-Phenanthridinone reduces NF-κB-induced transcription of the genes encoding TNF-α, IL-2, and IFN-γ in rat lymphocytes. In vivo, 6(5H)-phenanthridinone reduces spinal cord expression of inducible nitric oxide synthase (iNOS), IL-1β, TNF-α, IL-2, and IFN-γ and reduces disease score in a rat model of experimenta...
T78508	Delmitide acetate RDP-58 acetate	IFNAR	Immunology/Inflammation
	Delmitide acetate (RDP58) 是一种 d-异构体十肽，具有抗炎活性和口服活性。该化合物能够抑制 TNF-α、IFN-γ 以及白细胞介素 (IL)-12 的生成，同时提高血红素加氧酶 1 的活性，可用于针对溃疡性结肠炎的研究。
T64277	ODN 1585
	ODN 1585 是一种有效的 IFN 和 TNFα 产生诱导剂，也是一种 NK (natural killer) 的有效刺激剂，可用做疫苗佐剂。ODN 1585 能够增强 CD8+ T 细胞的功能，包括 CD8+ T 细胞介导的 IFN-γ 的产生。ODN 1585 可以诱导小鼠已建立的黑色素瘤消退，对小鼠的疟疾也表现出完全的保护作用。ODN 1585 能够用于研究急性骨髓性白血病 (AML) 和疟疾。
T38008	KBC-007
	KBC-007 is a synthetic branched chain-containing analog of α-galactosylceramide (α-GalCer). It induces IL-4 and IFN-γ secretion by mouse splenocytes when used at a concentration of 0.5 ng/ml and IL-2 secretion by DN32.D3 NKT hybridoma cells co-cultured with CD1d-transfected RBL cells pre-loaded with KBC-007 at a concentration of 8 ng/ml. KBC-007 (1 μg per animal) increases levels of IL-4, but not IFN-γ, to a similar degree as α-GalCer in mouse serum. KBC-007 (0.5 μg per animal) increases the sur...
T70291	PCC0208018
	PCC0208018 is a novel activator of effector T cells, enhancing T cell proliferation and activation to release interferon gamma (IFN-γ) and interleukin-2 (IL-2) without blocking the programmed cell death 1 (PD-1)/programmed cell death-ligand 1 (PD-L1) binding and not directly affecting tumor cell viability in vitro.
T75535	5-epi-Arvestonate A
	5-epi-Arvestonate A是一种从(Seriphidium transiliense)绢毛菊中提取的倍半萜化合物，能够通过激活(MITF)小眼相关转录因子和酪氨酸酶家族基因来促进黑色素的产生。此外，5-epi-Arvestonate A还能通过JAK/STAT信号通路，抑制永生化人角化细胞(HaCaT)中IFN-γ趋化因子的表达。
T68182	3-Hydroxykynurenamine
	3-Hydroxykynurenamine, also known as 3-Hydroxy-L-kynurenamine or 3-HKA, is a biogenic amine produced via an alternative pathway of tryptophan metabolism. In vitro, 3-HKA has an anti-inflammatory profile by inhibiting the IFN-γ mediated STAT1/NF-κΒ pathway in both mouse and human dendritic cells (DCs) with a consequent decrease in the release of pro-inflammatory chemokines and cytokines, most notably TNF, IL-6, and IL12p70. 3-HKA has protective effects in an experimental mouse model of psoriasis ...
TP1978	11R-VIVIT NFAT inhibitor, Cell Permeable
	NFAT inhibitor. Inhibits LPS or LPS plus IFN-γ-induced IL-12 p40, IL-12 p70, IL-23 and TNF secretion from bone marrow-derived macrophages (BMDMs). Also attenuates NO production and Nos2 mRNA expression in LPS-stimulated BMDMs. Improves symptoms in a mouse
T83846	HOXB7 (8-25) TFA Homeobox B7 (8-25)
	HOXB7 (8-25) 是 homeobox B7 (HOXB7) 的肽段，是细胞增殖的主要调控因子和肿瘤基因途径的激活剂。通过 HOXB7 (8-25) 肽脉冲的树突状细胞展示抗原，这些树突状细胞来源于分离的人类外周血单核细胞（PBMCs），刺激CD4+辅助T细胞的激活和IFN-γ的产生，从而引发特异性和多向性肿瘤反应性的抗肿瘤反应。
T26936	C188 Cpd188,STAT3-IN-C188,Cpd-188,C 188,C-188
	C188 is a cell-permeable naphthol compound and a STAT3 inhibitor. C188 inhibits IL-6-stimulated STAT3 Tyr705 phosphorylation and nuclear translocation in HepG2 cells by targeting STAT3 SH2 domain peptide-binding pocket, while exhibiting little effect agai
T76945	Cetrelimab
	Cetrelimab (JNJ 63723283; JNJ 3283) 为人源化IgG4κ单克隆抗体，专门针对PD-1。其与PD-1的结合Kd值为1.72 nM（在HEK293细胞中测得）。Cetrelimab有效阻断PD-1与其配体PD-L1和PD-L2的结合，其IC50值分别为111.7 ng/mL与138.6 ng/mL。此外，Cetrelimab能激活外周T细胞，提升细胞因子（IFN-γ, IL-2, TNF-α）的表达水平，进而抑制肿瘤在体内的生长。
T61071	AX-024
	AX-024 is a novel chemical compound that acts as an orally available inhibitor of the TCR-Nck interaction. Its primary mechanism of action is the selective inhibition of T cell activation triggered by TCR stimulation. With an IC50 value of approximately 1 nM, AX-024 effectively modulates cell signaling by specifically targeting SH3 domains. Additionally, AX-024 demonstrates desirable characteristics such as low acute toxicity, high potency, and excellent selectivity. Notably, it exhibits strong ...
T65390	Fluvoxketone
	Fluvoxketone is trifluoromethyl-substituted aryl ketone compound useful as an intermediate in the synthesis of Fluvoxamine, which is a selective serotonin reuptake inhibitor. In the synthesis of Fluvoxamine, the ketone carbonyl of Fluvoxketone is elaborated to an oxime.In vitro，the inhibitory effect of fluvoxamine on actin polymerization was concentration dependent, and its IC50 was approximately 30 μM.In vivo，fluvoxamine treated EAE rats showed a decrease in IFN-γ serum levels and an increase i...
TP1978L1	11R-VIVIT TFA (592517-80-1 Free base)
	11R-VIVIT TFA (592517-80-1 Free base) 是一种 NFAT 抑制剂。 11R-VIVIT TFA 抑制 LPS 或 LPS 加 IFN-γ 诱导的骨髓源性巨噬细胞 (BMDM) 分泌 IL-12 p40、IL-12 p70、IL-23 和 TNF。 11R-VIVIT TFA 减弱 LPS 刺激的 BMDM 中 NO 的产生和 Nos2 mRNA 的表达。 11R-VIVIT TFA 改善结肠炎小鼠模型的症状。 11R-VIVIT TFA 表现出免疫抑制作用并提高小鼠移植物的存活率。 11R-VIVIT TFA 具有细胞渗透性。
T83724	TPP-1 hydrochloride Targeting PD-L1 Peptide
	TPP-1是一种针对程序化细胞死亡蛋白1(PD-1)及其配体PD-1配体(PD-L1)之间蛋白-蛋白相互作用的肽抑制剂。它在无细胞实验中结合到PD-L1(Kd = 94.67 nM)。TPP-1 (20 µM)能逆转PD-L1在抗CD3激活的人类CD4+ T细胞中所引起的干扰素γ(IFN-γ)水平的下降。在使用HL-60白血病细胞与抗CD3激活的人类CD4+ T细胞共培养并在植入前预处理时，以4 mg/kg的剂量给药，可减少小鼠异种移植模型中的肿瘤体积。
T79487	MAO A/HSP90-IN-2	Monoamine Oxidase	Neuroscience
	MAO A/HSP90-IN-2（compound 4-C）是一种针对HSP90和MAO A的双重抑制剂，显示出分别对这两种酶有0.016 μM和4.58 μM的IC50值。该化合物能够上调HSP70，降低HER2和磷酸化AKT的表达，同时能减少GL26细胞中由IFN-γ诱导的PD-L1表达增加。此外，MAO A/HSP90-IN-2能够抑制对Temozolomide敏感或耐药的胶质母细胞瘤(GBM)、结肠癌、白血病和非小细胞肺癌细胞的生长，并可能有助于阻止肿瘤逃避免疫监控。
T35708	N-acetyl-5-Aminosalicylic Acid
	N-acetyl-5-Aminosalicylic acid is a metabolite of the anti-inflammatory agent 5-aminosalicylic acid and its prodrug form, sulfasalazine . It is formed in the liver, intestinal lumen, and colonic epithelial cells via N-acetyltransferases. It reduces IFN-γ binding to colonic epithelial cells by 24% when used at a concentration of 10 mM. N-acetyl-5-Aminosalicylic acid (100 μM) scavenges 2,2-diphenyl-1-picrylhydrazyl radicals in a cell-free assay and inhibits base hydroxylation in DNA stimulated by ...
T82071	Influenza NP (311-325)
	Influenza NP (311-325) 是具有生物活性的肽段，对应于流感病毒核蛋白(NP)的311至325氨基酸。作为MHC II类限制性表位，它用于研究宿主在感染期间的免疫响应。该肽能在细胞内细胞因子检测中诱导强烈的γ干扰素(IFN-γ)产生，但不激活小鼠CD8 T细胞。谷氨酰胺(Q)或谷氨酸(E)位于N端时，焦谷氨酰(pGlu)肽可自发形成。Q或E向pGlu的自然转化及其疏水性γ-内酰胺环在肽的胃肠道蛋白酶稳定性中可能起作用。焦谷氨酰肽作为常见肽的一部分，在HPLC分析中评估肽的纯度。
T83700	IRBP (651-670) (human) TFA IRBP651-670,Interphotoreceptor Retinoid-Binding Protein (651-670)
	IRBP651-670（Interphotoreceptor retinoid-binding protein (651-670)）是IRBP（亦称为retinoid-binding protein 3）的肽段，参与色素再生，通过将视黄醇和视黄醛从光感受细胞传输到视网膜色素上皮。在C57BL/6小鼠中，利用IRBP651-670诱导自身免疫性葡萄膜炎，这些小鼠携带H-2b单体型。用IRBP651-670（300 µg/动物）免疫增加了小鼠眼部IL-1β、IL-6、IL-17、TNF-α和IFN-γ水平，免疫细胞浸润及光感受器损伤。
T83681	IRBP (1-20) (human, rat) TFA IRBP1-20,Interphotoreceptor Retinoid-Binding Protein (1-20)
	IRBP1-20（1-20）是IRBP的一个十二肽片段，亦称视黄醇结合蛋白3，负责运输视锥细胞中的视黄醇和视黄醛至视网膜色素上皮，参与色素再生。在携带H-2b等位基因型的C57BL/6小鼠中，IRBP1-20用于诱导自身免疫性葡萄膜视网膜炎。IRBP1-20（3 µM）能增加初级小鼠脾淋巴细胞分泌IL-4、IL-5和IL-6的水平。用IRBP1-20免疫并再次挑战，可增加IFN-γ缺乏小鼠的耳部肿胀、眼部血管炎症、免疫细胞浸润和视锥细胞层损伤，以及视网膜脱落。
T83852	EGFRvIII Peptide TFA PEGFRvIII (9-mer),Epidermal Growth Factor Receptor Variant III Peptide
	EGFRvIII peptide是一种合成肽，对应于特异性肿瘤、具有持续激活性的EGFR变体EGFRvIII的融合接头，该变体缺少野生型EGFR的第6至273个氨基酸。在25 µg/ml的浓度下，它能与MHC I类亚型HLA-A0201阳性的T2细胞结合。在用于分离的人外周血单个核细胞（PBMCs）衍生的树突状细胞中，EGFRvIII peptide可诱导抗原呈递，进而刺激CD8+细胞毒性T淋巴细胞的激活和IFN*-γ产生。与toll样受体5（TLR5）激动剂鞭毛蛋白B共同免疫EGFRvIII peptide（15 µg/动物），在正交GL261胶质母细胞瘤小鼠异种移植模型中，增加了CD8+ T细胞数量，减少了调节性T细胞（Tregs）数量，减少了肿瘤体积，并提高了生存率。

化合物

Cat.No: T9043

Target: P450, STAT

(R)-Lisofylline

Cat.No: T21694

Synonym: (R)-Lisophylline

Target: STAT

(Rac)-Benpyrine

Cat.No: T8692

Target: TNF

PD-1/PD-L1-IN-10

Cat.No: T9616

Target: PD-1/PD-L1

Cat.No: T1781

Synonym: GW 9508

Target: GPR, Potassium Channel

IFN-γ Antagonist 1

Cat.No: T76637

TNF/IFNγ-IN-1

Cat.No: T83628

Target: Antioxidant, TNF, COX

IFN-γ Antagonist 1 acetate

Cat.No: T76638

IFN alpha-IFNAR-IN-1 hydrochloride

Cat.No: T11630

Target: Others, IFNAR

Cat.No: T38158

Anti-Mouse IFN gamma Antibody (H22)

Cat.No: T78262

Target: IFNAR

Cat.No: T76742

Synonym: NI-0501

Target: COX

N-alpha-Tosyl-L-lysine chloromethyl ketone hydrochloride

Cat.No: T16169

Synonym: N-alpha-Tosyl-L-lysine_chloromethyl_ketone_hydrochloride

Target: Others, Proteasome, COX

AX-024 hydrochloride

Cat.No: T4403

Synonym: AX-024 HCl

Target: IL Receptor, TNF, COX, IFNAR, Interleukin

Cat.No: T76691

Target: IFNAR, Chk

2-(1,8-naphthyridin-2-yl)phenol

Cat.No: T2168

Target: STAT

Cat.No: T13063

Target: MyD88

15-LOX-1 inhibitor 1

Cat.No: T36169

Cat.No: T64280

1-Isopropyltryptophan

Cat.No: T79189

Synonym: 1-IsoPT

Target: Indoleamine 2,3-Dioxygenase (IDO)

Cat.No: T16570

Synonym: VX-740,HMR 3480

Target: Others

Cat.No: T71839

Cat.No: T81840

CFP10 (71–85)

Cat.No: T82743

Cat.No: T26895

Synonym: BRD-0476,ML 187,ML187,ML-187,BRD 0476

Phenylpyropene C

Cat.No: T62726

Cat.No: T22506

Target: NOS

(Rac)-Indoximod

Cat.No: T60266

PD-1/PD-L1-IN-31

Cat.No: T78755

Target: PD-1/PD-L1

6(5H)-Phenanthridinone

Cat.No: T72017

Delmitide acetate

Cat.No: T78508

Synonym: RDP-58 acetate

Target: IFNAR

Cat.No: T64277

Cat.No: T38008

Cat.No: T70291

5-epi-Arvestonate A

Cat.No: T75535

3-Hydroxykynurenamine

Cat.No: T68182

Cat.No: TP1978

Synonym: NFAT inhibitor, Cell Permeable

HOXB7 (8-25) TFA

Cat.No: T83846

Synonym: Homeobox B7 (8-25)

Cat.No: T26936

Synonym: Cpd188,STAT3-IN-C188,Cpd-188,C 188,C-188

Cat.No: T76945

Cat.No: T61071

Cat.No: T65390

11R-VIVIT TFA (592517-80-1 Free base)

Cat.No: TP1978L1

TPP-1 hydrochloride

Cat.No: T83724

Synonym: Targeting PD-L1 Peptide

MAO A/HSP90-IN-2

Cat.No: T79487

Target: Monoamine Oxidase

N-acetyl-5-Aminosalicylic Acid

Cat.No: T35708

Influenza NP (311-325)

Cat.No: T82071

IRBP (651-670) (human) TFA

Cat.No: T83700

Synonym: IRBP651-670,Interphotoreceptor Retinoid-Binding Protein (651-670)

IRBP (1-20) (human, rat) TFA

Cat.No: T83681

Synonym: IRBP1-20,Interphotoreceptor Retinoid-Binding Protein (1-20)

EGFRvIII Peptide TFA

Cat.No: T83852

Synonym: PEGFRvIII (9-mer),Epidermal Growth Factor Receptor Variant III Peptide

Cat. No.	Product Name	Target	Signaling Pathways
TN2539	1beta-Hydroxyalantolactone	IL Receptor; TNF	Apoptosis; Immunology/Inflammation
	1beta-Hydroxyalantolactone 是从药用植物大英花的花头中分离出的小分子化合物，可抑制细胞中TNF-α、IL-17、IFN-γ的表达，促进TNF-α、IFN-γ、IL-17的分泌，可防治类风湿性关节炎。
T5681	ETHYL CAFFEATE 咖啡酸乙酯,ETHYL 3,4-DIHYDROXYCINNAMATE	NF-κB; COX; PGE Synthase; NO Synthase	Immunology/Inflammation; Neuroscience; NF-κB
	Ethyl Caffeate (ETHYL 3,4-DIHYDROXYCINNAMATE) 是从鬼针草分离的一种酚类天然产物，在体外或在小鼠皮肤中抑制NF-κB 活化及其下游炎症介质的诱导型一氧化氮合酶、环氧合酶 2 和前列腺素 E2。
T37280	PE(18:1(9Z)/0:0)	Endogenous Metabolite	Metabolism
	PE(18:1(9Z)/0:0) 是一种天然存在的溶血磷脂，是缩醛磷脂溶血磷脂酰乙醇胺的类似物。 PE(18:1(9Z)/0:0) 以浓度依赖性方式诱导 PC12 大鼠神经元细胞中细胞内钙的瞬时增加。 PE(18:1(9Z)/0:0) 增加 IL-4 和 IL-2 的产生，但不增加 IFN-γ 的产生。在小鼠血清中，PE(18:1(9Z)/0:0)（1 μg/动物）诱导 T 辅助细胞 2 反应。在寒冷暴露三天后，小鼠肩胛间棕色脂肪组织中的 PE(18:1(9Z)/0:0) 水平增加。
T14854	Caerulomycin A 浅蓝霉素,Cerulomycin,Caerulomycin	Antifungal	Microbiology/Virology
	Caerulomycin A (Caerulomycin) 是抗真菌和抗细菌化合物，能够诱导 T 细胞的产生。它能够抑制 IFN-γ 诱导的 STAT1 通路，从而增强 TGF-β-Smad3 信号通路。它可用于自身免疫病的研究。
T6S0139	Neobavaisoflavone	Apoptosis; DNA/RNA Synthesis	Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Neobavaisoflavone 是一种从Psoralea corylifolia 的种子中分离出来的类黄酮。它具有抗炎，抗癌和抗氧化的作用。它在中至高浓度下可抑制 DNA 聚合酶，也可抑制血小板聚集。
T3829	Ginsenoside F3 人参皂苷F3	Others; IFNAR; Interleukin	Immunology/Inflammation; Others
	Ginsenoside F3 是一种皂苷，提取自Panax ginseng 叶片。它能够调节1 型 (IL-2, IFN-γ) 及 2 型细胞因子(IL-4 and IL-10) 的产生和表达，有免疫增强的作用。
T3824	Jaceosidin	Apoptosis; BCL; COX; UGT	Apoptosis; Immunology/Inflammation; Metabolism; Neuroscience
	Jaceosidin 是从毛莲蒿中得到的一种黄酮类天然产物，可激活Bax，下调 Mcl-1 和 c-FLIP 的表达，诱导癌细胞凋亡。它能够降低炎性因子水平，激活 NF-κB，抑制COX-2的表达，具有抗癌和抗炎作用。
T6677	Sophocarpine	ERK; p38 MAPK; NF-κB; TLR; COX; HER; JNK; STAT	Angiogenesis; Immunology/Inflammation; JAK/STAT signaling; MAPK; Neuroscience; NF-κB; Stem Cells; Tyrosine Kinase/Adaptors
	Sophocarpine 是一种从传统草药苦参中提取的重要生物碱。苦参具有抗病毒、抗肿瘤和抗炎等多种药理作用。它通过多种机制显著抑制癌细胞的生长，具有抗肿瘤活性。
TN5233	Villosin	Others	Others
	Villosin exhibits potent cytotoxic activity , it may be used as a potential lead molecule for antitumor therapeutic development. Villosin shows inhibitory effects against nitric oxide production in LPS and IFN-γ-induced RAW 264.7 murine macrophages with I
T35895	Ingenol 3,20-dibenzoate
	Ingenol 3,20-dibenzoate is a powerful activator of protein kinase C (PKC) isoforms. It effectively induces the translocation of nPKC-delta, -epsilon, and -theta as well as PKC-mu from the cytosolic fraction to the particulate fraction. Through de novo synthesis of macromolecules, it triggers apoptosis with characteristic morphology. Moreover, Ingenol 3,20-dibenzoate enhances IFN-γ production and degranulation in NK cells, particularly when stimulated by NSCLC cells[1][2].
TN4959	Schizandriside	Prostaglandin Receptor	GPCR/G Protein; Immunology/Inflammation
	Schizandriside may have anti-inflammatory effects, it has inhibitory activities against nitric oxide and prostaglandin E(2) production in IFN-γ- and lipopolysaccharide-stimulated RAW 264.7 cells. It shows significant cytotoxicity against A549, SK-OV-3, SK

天然产物

1beta-Hydroxyalantolactone

Cat.No: TN2539

Target: IL Receptor, TNF

Cat.No: T5681

Synonym: 咖啡酸乙酯,ETHYL 3,4-DIHYDROXYCINNAMATE

Target: NF-κB, COX, PGE Synthase, NO Synthase

PE(18:1(9Z)/0:0)

Cat.No: T37280

Target: Endogenous Metabolite

Cat.No: T14854

Synonym: 浅蓝霉素,Cerulomycin,Caerulomycin

Target: Antifungal

Neobavaisoflavone

Cat.No: T6S0139

Target: Apoptosis, DNA/RNA Synthesis

Cat.No: T3829

Synonym: 人参皂苷F3

Target: Others, IFNAR, Interleukin

Cat.No: T3824

Target: Apoptosis, BCL, COX, UGT

Cat.No: T6677

Target: ERK, p38 MAPK, NF-κB, TLR, COX, HER, JNK, STAT

Cat.No: TN5233

Target: Others

Ingenol 3,20-dibenzoate

Cat.No: T35895

Cat.No: TN4959

Target: Prostaglandin Receptor

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-03356	IFN gamma Protein, Mouse, Recombinant IFN γ,interferon, γ,interferon, g...	Mouse	HEK293 Cells
	IFN gamma Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 15.5 kDa and the accession number is A0A7R8C347.
TMPY-01714	IFN gamma Protein, Human, Recombinant IFI,interferon, γ,IFN γ,IFG,I...	Human	CHO Cells
	IFN gamma Protein, Human, Recombinant is expressed in CHO mammalian cells. The predicted molecular weight is 16.7 kDa and the accession number is A0A7R8GUN6.
TMPK-00047	IFN gamma Protein, Human, Recombinant (His & Avi) IFN gamma,interferon,Interferon-γ,γ	Human	HEK293 Cells
	Interferon-gamma (IFN gamma) is a cytokine that plays physiologically important roles in promoting innate and adaptive immune responses. The absence of IFN gamma production or cellular responsiveness in humans and experimental animals significantly predisposes the host to microbial infection, a result that validates the physiologic importance of this cytokine in preventing infectious disease. IFN gamma Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi ...
TMPY-06983	IFN gamma Protein, Human, Recombinant (E. coli) Interferon Gamma,IFN γ,IFN gamma,...	Human	E. coli
	IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte effector T cells once antigen-specific immunity develops. IFN gamma has antiviral, immunoregulatory, and anti-tumor properties. IFNG, in addition to having antiviral activity, has important immunoregulatory functions, it is a potent activ...
TMPY-02827	IFN gamma Protein, Rat, Recombinant (hFc) interferon, γ,干扰素,interferon, gamma,IFN	Rat	HEK293 Cells
	IFN gamma Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.5 kDa and the accession number is P01581.
TMPY-02355	IFNGR1 Protein, Mouse, Recombinant (His) interferon gamma receptor 1,Nktar,interferon γ rece...	Mouse	HEK293 Cells
	IFNGR1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.4 kDa and the accession number is P15261.
TMPY-02323	IFN gamma Protein, Mouse, Recombinant (His) IFN-g,Ifg,干扰素,interferon, γ,interferon, ga...	Mouse	HEK293 Cells
	IFN gamma Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17 kDa and the accession number is P01580.
TMPY-02322	IFN gamma Protein, Mouse, Recombinant (hFc) IFN γ,Ifg,IFN-g,interferon, gamma...	Mouse	HEK293 Cells
	IFN gamma Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.5 kDa and the accession number is P01580.
TMPK-00048	IFN gamma Protein, Human, Recombinant (His & Avi), Biotinylated IFNγ,IFN γ/IFNG...	Human	HEK293 Cells
	Interferon-gamma (IFN gamma) is a cytokine that plays physiologically important roles in promoting innate and adaptive immune responses. The absence of IFN gamma production or cellular responsiveness in humans and experimental animals significantly predisposes the host to microbial infection, a result that validates the physiologic importance of this cytokine in preventing infectious disease. IFN gamma Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells w...
TMPY-03664	IFN gamma Protein, Ferret, Recombinant (His) interferon, gamma,interferon, γ,IFN γ<...	Ferret	HEK293 Cells
	IFN gamma Protein, Ferret, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.4 kDa and the accession number is A4PIZ9.
TMPY-00527	IFN gamma Protein, Rhesus, Recombinant interferon, gamma,干扰素,IFN γ,interferon,	Rhesus	E. coli
	IFN gamma Protein, Rhesus, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 16.9 kDa and the accession number is G7N7K9.
TMPY-04191	IFN gamma Protein, Rhesus, Recombinant (His) interferon, γ,IFN γ,干扰素,interfero...	Rhesus	HEK293 Cells
	IFN gamma Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 18.2 kDa and the accession number is G7N7K9.
TMPY-03145	IFN-beta Protein, Human, Recombinant IFN-β,interferon, β1, fibroblast,IFNB,IFB,...	Human	CHO Cells
	IFN-beta Protein, Human, Recombinant is expressed in CHO mammalian cells. The predicted molecular weight is 20 kDa and the accession number is P01574.
TMPY-03467	IFN-beta Protein, Mouse, Recombinant Ifb,IFN-β,interferon, beta 1, fibroblast,干扰素,IF...	Mouse	HEK293 Cells
	IFN-beta Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 20.3 kDa and the accession number is P01575.
TMPY-03072	IFN-omega Protein, Human, Recombinant (His) IFN-ω,IFN-ω 1,interferon omega-1,IFN	Human	HEK293 Cells
	IFN-omega Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21.6 kDa and the accession number is P05000.
TMPY-00831	IFN-beta Protein, Human, Recombinant (hFc) IFNB,IFN-β,Interferon beta,interferon, bet...	Human	HEK293 Cells
	IFN-beta Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.7 kDa and the accession number is A0A7R8GV38.
TMPJ-01056	IL-18 Protein, Mouse, Recombinant (His) Interferon γ-inducing factor,Interleukin-1 gamma,Ig...	Mouse	E. coli
	Interleukin-18 (IL-18）is a protein which belongs to the IL-1 family. It is expressed as a 24 kDa precursor by endothelial and epithelial cells, keratinocytes, gamma δ T cells, and phagocytes. Mature mouse IL-18 shares 63% and 91% amino acid sequence identity with mouse and rat IL-18, respectively. IL-18 binds to the widely expressed IL-18 R alpha which recruits IL-18 R beta to form the signaling receptor complex. Its bioactivity is negatively regulated by interactions with IL-18 binding proteins...
TMPY-02354	IFNGR1 Protein, Mouse, Recombinant (hFc) IFN-gammaR,Ifgr,interferon γ receptor 1,	Mouse	HEK293 Cells
	IFNGR1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 53 kDa and the accession number is P15261.
TMPJ-00070	IL-18 Protein, Human, Recombinant (His) GIF,IL-1 γ,白细胞介素,Iboctadekin,Interleukin-18,Interfe...	Human	HEK293 Cells
	Interleukin-18 is a secreted protein and it belongs to the IL-1 family. IL-18 is a proinflammatory cytokine and produced by macrophages and other cells. This cytokine can induce the IFN-gamma production of T cells. The combination of this cytokine and IL12 has been shown to inhibit IL-4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL-18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its biological activity. After...
TMPJ-00745	IFN-alpha 2a/IFNA2 Protein, Human, Recombinant Interferon α-2,IFNA2,干扰素,IFN α2a,IFN	Human	E. coli
	At least 23 different variants of IFN-α are known. The individual proteins have molecular masses between 19-26 kDa and consist of proteins with lengths of 156-166 and 172 amino acids. All IFN-α subtypes possess a common conserved sequence region between amino acid positions 115-151 while the amino-terminal ends are variable. Many IFN-α subtypes only differ in their sequences by one or two positions. Naturally occurring variants also include proteins truncated by 10 amino acids at the carboxy-ter...
TMPJ-00746	IFN-alpha 2b/IFNA2 Protein, Human, Recombinant 干扰素,IFNA2,Interferon α-2,Interferon α-A,Interferon ...	Human	E. coli
	At least 23 different variants of IFN-α are known. The individual proteins have molecular masses between 19-26 kDa and consist of proteins with lengths of 156-166 and 172 amino acids. All IFN-α subtypes possess a common conserved sequence region between amino acid positions 115-151 while the amino-terminal ends are variable. Many IFN-α subtypes differ in their sequences by only one or two positions. Naturally occurring variants also include proteins that are truncated by 10 amino acids at the ca...
TMPY-02456	IFN-beta Protein, Mouse, Recombinant (hFc) Ifb,interferon, β1, fibroblast,IFN-β,干扰素,interferon...	Mouse	HEK293 Cells
	IFN-beta Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.7 kDa and the accession number is P01575.
TMPH-03495	IFN gamma Protein, Sheep, Recombinant (His)	Sheep	P. pastoris (Yeast)
	IFN gamma Protein, Sheep, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 18.9 kDa and the accession number is P17773.
TMPH-00373	IFN gamma Protein, Chicken, Recombinant (GST)	Chicken	E. coli
	Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. IFN gamma Protein, Chicken, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 43.7 kDa and the ac...
TMPY-03828	IFN-beta Protein, Rhesus, Recombinant (mFc) interferon, beta 1, fibroblast,干扰素,interferon, β1, fibroblas...	Rhesus	HEK293 Cells
	IFN-beta Protein, Rhesus, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 46.4 kDa and the accession number is G7NFX1.
TMPH-00775	IFN gamma Protein, Goat, Recombinant (His & Myc)	Goat	E. coli
	Type II interferon produced by immune cells such as T-cells and NK cells that plays crucial roles in antimicrobial, antiviral, and antitumor responses by activating effector immune cells and enhancing antigen presentation. Primarily signals through the JAK-STAT pathway after interaction with its receptor IFNGR1 to affect gene regulation. Upon IFNG binding, IFNGR1 intracellular domain opens out to allow association of downstream signaling components JAK2, JAK1 and STAT1, leading to STAT1 activati...
TMPH-00374	IFN-beta Protein, Chicken, Recombinant (His)	Chicken	E. coli
	Has antiviral activities. IFN-beta Protein, Chicken, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 24.8 kDa and the accession number is Q90873.
TMPY-00833	IFN-omega Protein, Human, Recombinant (hFc) 干扰素,IFNW1,IFN-ω 1,interferon ω-1,IFN	Human	HEK293 Cells
	IFN-omega Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.6 kDa and the accession number is A0A7R8GUW6.
TMPH-02451	IFN gamma Protein, Marmota monax, Recombinant (His)	Marmota monax	P. pastoris (Yeast)
	Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. IFN gamma Protein, Marmota monax, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 18.6 kDa and the accession numb...
TMPH-00778	IFN gamma Protein, Guinea Pig, Recombinant (His)	Guinea pig	E. coli
	IFN gamma Protein, Guinea Pig, Recombinant (His) is expressed in E. coli.
TMPH-00277	IFN-omega Protein, Bovine, Recombinant (His & SUMO)	Bovine	E. coli
	IFN-omega Protein, Bovine, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 35.7 kDa and the accession number is P07352.
TMPY-02347	IFN-alpha 13/IFNA13 Protein, Mouse, Recombinant (hFc) interferon, alpha 13,RP23-139P14.1,IFN-α 13,干扰素,int...	Mouse	HEK293 Cells
	IFN-alpha 13/IFNA13 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 47.5 kDa and the accession number is Q80SU4.
TMPH-03494	IFN gamma Protein, Sheep, Recombinant (E. coli, His)	Sheep	E. coli
	IFN gamma Protein, Sheep, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 20.9 kDa and the accession number is P17773.
TMPJ-00747	IFN-alpha 2/IFNA2 Protein, Mouse, Recombinant IFN-Alpha-2,Interferon α-A,IFN α2,LeIF A,干...	Mouse	E. coli
	At least 23 different variants of Interferon-α are known. The individual proteins have molecular masses between 19-26 kD and consist of proteins with lengths of 156-166 and 172 amino acids. All IFN-α subtypes possess a common conserved sequence region between amino acid positions 115-151 while the amino-terminal ends are variable. Many IFN-α subtypes differ in their sequences at only one or two positions. Naturally occurring variants also include proteins truncated by 10 amino acids at the carbo...
TMPK-00075	IFN-alpha 1/IFNA1 Protein, Human, Recombinant (hFc) IFN-α-1/13,IFN α1,IFN alpha1,干扰素,...	Human	HEK293 Cells
	IFN-α, a cytokine expressed in human islets from individuals affected by type 1 diabetes, plays a key role in the pathogenesis of diabetes by upregulating inflammation, endoplasmic reticulum (ER) stress and MHC class I overexpression, three hallmarks of islet histology in early type 1 diabetes. IFN-alpha 1/IFNA1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 46.14 kDa and the accession number is P01562.
TMPY-03320	IFN-alpha 13/IFNA13 Protein, Cynomolgus, Recombinant (hFc) IFN-α 13,干扰素,interferon, alpha 13,IFNA13,i...	Cynomolgus	HEK293 Cells
	IFN-alpha 13/IFNA13 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.4 kDa and the accession number is G7NFW4.
TMPY-03375	IFN-alpha 13/IFNA13 Protein, Cynomolgus, Recombinant (His) IFNA13,干扰素,interferon, α13,interferon, alpha 13,	Cynomolgus	HEK293 Cells
	IFN-alpha 13/IFNA13 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.8 kDa and the accession number is G7NFW4.
TMPK-00074	IFN-alpha 1/IFNA1 Protein, Mouse, Recombinant (hFc) IFN-α-1/13,IFN alpha1,干扰素,Interferon α-1/1...	Mouse	HEK293 Cells
	IFN-α, a cytokine expressed in human islets from individuals affected by type 1 diabetes, plays a key role in the pathogenesis of diabetes by upregulating inflammation, endoplasmic reticulum (ER) stress and MHC class I overexpression, three hallmarks of islet histology in early type 1 diabetes. IFN-alpha 1/IFNA1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 45.88 kDa and the accession number is P01572.
TMPJ-00780	IFN-alpha 6/IFNA6 Protein, Human, Recombinant (His) Interferon α-K,Interferon α-6,IFN α6,Interferon α-5...	Human	HEK293 Cells
	Interferon α-6 (IFN-α6) is a secreted protein which belongs to the α/β interferon family. IFN-α6 is produced by macrophages, expressed at low level, only 1.0% of the average gene in this release. IFN-α6 contains interferon alpha, beta and delta domain. IFN-α has antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.
TMPY-03891	IFN-alpha 13/IFNA13 Protein, Mouse, Recombinant (His) IFN-α 13,干扰素,interferon, alpha 13,interferon, α13,R...	Mouse	HEK293 Cells
	IFN-alpha 13/IFNA13 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.5 kDa and the accession number is Q80SU4.
TMPK-00076	IL-18 Protein (Primary Amine Labeling), Human, Recombinant, Biotinylated 白介素,IL-18,白细胞介素,IL18,IL-1F4,IL-1g,IL1F4,IL-1 gamma,Interleuk...	Human	E. coli
	Interleukin (IL)-18 was originally discovered as a factor that enhanced IFN-γ production from anti-CD3-stimulated Th1 cells, especially in the presence of IL-12. Upon stimulation with Ag plus IL-12, naïve T cells develop into IL-18 receptor (IL-18R) expressing Th1 cells, which increase IFN-γ production in response to IL-18 stimulation.
TMPK-00317	IL-18R alpha Protein, Human, Recombinant (His & Avi), Biotinylated IL-18 R α,IL-1 R5,IL18Ra,IL-18Ra,CD218a,IL-18 R alpha,IL-1 R...	Human	HEK293 Cells
	Interleukin-18 (IL-18) is a member of the interleukin-1 family of cytokines produced constitutively by different cell types and by adipose tissue. Interleukin (IL)-18 was originally discovered as a factor that enhanced IFN-γ production from anti-CD3-stimulated Th1 cells, especially in the presence of IL-12. Upon stimulation with Ag plus IL-12, naïve T cells develop into IL-18 receptor (IL-18R) expressing Th1 cells, which increase IFN-γ production in response to IL-18 stimulation. IL-18R alpha Pr...
TMPK-00512	IL-18R alpha Protein, Cynomolgus, Recombinant (aa 22-329, His) IL18R1,IL-1 Rrp,CD218a,IL18Ra,IL-18Ra,IL-18 R alpha,IL1RRP,I...	Cynomolgus	HEK293 Cells
	Interleukin-18 (IL-18) is a member of the interleukin-1 family of cytokines produced constitutively by different cell types and by adipose tissue. Interleukin (IL)-18 was originally discovered as a factor that enhanced IFN-γ production from anti-CD3-stimulated Th1 cells, especially in the presence of IL-12. Upon stimulation with Ag plus IL-12, naïve T cells develop into IL-18 receptor (IL-18R) expressing Th1 cells, which increase IFN-γ production in response to IL-18 stimulation. IL-18R alpha Pr...
TMPK-00316	IL-18R alpha Protein, Human, Recombinant (His & Avi) CD218a,IL-18 R1,IL1RRP,IL-18Ra,IL-18 R alpha,IL-1 Rrp,IL-1 R...	Human	HEK293 Cells
	Interleukin-18 (IL-18) is a member of the interleukin-1 family of cytokines produced constitutively by different cell types and by adipose tissue. Interleukin (IL)-18 was originally discovered as a factor that enhanced IFN-γ production from anti-CD3-stimulated Th1 cells, especially in the presence of IL-12. Upon stimulation with Ag plus IL-12, naïve T cells develop into IL-18 receptor (IL-18R) expressing Th1 cells, which increase IFN-γ production in response to IL-18 stimulation. IL-18R alpha Pr...
TMPJ-00008	CXCL10 Protein, Human, Recombinant (hFc & His) INP10,10 kDa Interferon Gamma-Induced Protein,C-X-C Motif Ch...	Human	HEK293 Cells
	Human C-X-C Motif Chemokine Ligand 10 (CXCL10) is a non-ELR chemokine secreted by various cell types, such as monocytes, endothelial cells and fibroblasts, in response to IFN-γ. CXCL10 functions via chemokine receptor CXCR3. CXCL10 has been attributed to several roles, such as chemoattraction for activated T-lymphocytes, inhibition of angiogenesis, and antitumor activity.
TMPJ-00177	BAFF/TNFSF13B Protein, Human, Recombinant (Avi & hFc), Biotinylated BAFF,Dendritic cell-derived TNF-like molecule,CD257,B lympho...	Human	HEK293 Cells
	B-cell activating factor (BAFF), also known as BLyS, TALL-1, THANK, and TNFSF13B, is a transmembrane glycoprotein in the TNF ligand superfamily. BAFF is a cytokine and serves as a ligand for receptors TNFRSF13B (TACI), TNFRSF17 (BCMA), and TNFRSF13C (BAFFR). BAFF can promotes the survival, proliferation and maturation of B lymphocytes, which are key elements in the pathogenesis of systemic lupus erythematosus (SLE). This cytokine is encoded on TNFSF13B gene, and diverse single-nucleotide polymor...
TMPJ-00218	SLAMF6 Protein, Human, Recombinant (His & Avi), Biotinylated CD352,SLAM Family Member 6,Activating NK Receptor,NTB-A,KALI...	Human	HEK293 Cells
	SLAM Family Member 6 (SLAMF6) is a 60 kD single-pass type I membrane protein that belongs to the SLAM subgroup of the CD2 family. Human SLAMF6/ NTB-A contains a 205 amino acid extracellular domain (ECD) with one Ig-like V-set and one Ig-like C2-set domain, a 21 amino acid transmembrane segment and an 84 amino acid cytoplasmic domain, with two immunoreceptor tyrosine-based switch motifs. SLAMF6 is a homodimer. SLAMF6 can interact with PTN6 and, upon phosphorylation, with PTN11 and SH2D1A/SAP. Pho...
TMPJ-00181	PD-1 Protein, Human, Recombinant (His & Avi), Biotinylated Programmed cell death protein 1,PDCD1,CD279,hPD-1	Human	HEK293 Cells
	Programmed cell death protein 1(PDCD1) is a single-pass type I membrane protein and contains 1 Ig-like V-type domain. PD-1 is a member of the extended CD28/CTLA-4 family of T cell regulators. PDCD1 inhibits the T-cell proliferation and production of related cytokines including IL-1, IL-4, IL-10 and IFN-γ by suppressing the activation and transduction of PI3K/AKT pathway. In addition, coligation of PDCD1 inhibits BCR-mediating signal by dephosphorylating key signal transducer. PDCD1 has been sugg...
TMPJ-01337	IL-21R Protein, Mouse, Recombinant (aa 20-236, His) Nilr,IL-21R,Interleukin-21 receptor,IL-21 receptor,Il21r	Mouse	HEK293 Cells
	Interleukin-21 receptor (IL-21R) is a type I transmembrane glycoprotein within the class I cytokine receptor family, type 4 subfamily. IL-21R is expressed mainly on B cells, NK cells, and activated T cells, but is also found on dendritic cells, alternatively activated macrophages, intestinal lamina propria fibroblasts and epithelial cells, and keratinocytes. Both IL-21 and IL-4 are necessary for efficient B cell IgG1 production and normal germinal center architecture. B cell IL-21 R engagement i...

重组蛋白

IFN gamma Protein, Mouse, Recombinant

Cat.No: TMPY-03356

Species: Mouse

Expression System: HEK293 Cells

IFN gamma Protein, Human, Recombinant

Cat.No: TMPY-01714

Species: Human

Expression System: CHO Cells

IFN gamma Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00047

Species: Human

Expression System: HEK293 Cells

IFN gamma Protein, Human, Recombinant (E. coli)

Cat.No: TMPY-06983

Species: Human

Expression System: E. coli

IFN gamma Protein, Rat, Recombinant (hFc)

Cat.No: TMPY-02827

Species: Rat

Expression System: HEK293 Cells

IFNGR1 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-02355

Species: Mouse

Expression System: HEK293 Cells

IFN gamma Protein, Mouse, Recombinant (His)

Cat.No: TMPY-02323

Species: Mouse

Expression System: HEK293 Cells

IFN gamma Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-02322

Species: Mouse

Expression System: HEK293 Cells

IFN gamma Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00048

Species: Human

Expression System: HEK293 Cells

IFN gamma Protein, Ferret, Recombinant (His)

Cat.No: TMPY-03664

Species: Ferret

Expression System: HEK293 Cells

IFN gamma Protein, Rhesus, Recombinant

Cat.No: TMPY-00527

Species: Rhesus

Expression System: E. coli

IFN gamma Protein, Rhesus, Recombinant (His)

Cat.No: TMPY-04191

Species: Rhesus

Expression System: HEK293 Cells

IFN-beta Protein, Human, Recombinant

Cat.No: TMPY-03145

Species: Human

Expression System: CHO Cells

IFN-beta Protein, Mouse, Recombinant

Cat.No: TMPY-03467

Species: Mouse

Expression System: HEK293 Cells

IFN-omega Protein, Human, Recombinant (His)

Cat.No: TMPY-03072

Species: Human

Expression System: HEK293 Cells

IFN-beta Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00831

Species: Human

Expression System: HEK293 Cells

IL-18 Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-01056

Species: Mouse

Expression System: E. coli

IFNGR1 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-02354

Species: Mouse

Expression System: HEK293 Cells

IL-18 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00070

Species: Human

Expression System: HEK293 Cells

IFN-alpha 2a/IFNA2 Protein, Human, Recombinant

Cat.No: TMPJ-00745

Species: Human

Expression System: E. coli

IFN-alpha 2b/IFNA2 Protein, Human, Recombinant

Cat.No: TMPJ-00746

Species: Human

Expression System: E. coli

IFN-beta Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-02456

Species: Mouse

Expression System: HEK293 Cells

IFN gamma Protein, Sheep, Recombinant (His)

Cat.No: TMPH-03495

Species: Sheep

Expression System: P. pastoris (Yeast)

IFN gamma Protein, Chicken, Recombinant (GST)

Cat.No: TMPH-00373

Species: Chicken

Expression System: E. coli

IFN-beta Protein, Rhesus, Recombinant (mFc)

Cat.No: TMPY-03828

Species: Rhesus

Expression System: HEK293 Cells

IFN gamma Protein, Goat, Recombinant (His & Myc)

Cat.No: TMPH-00775

Species: Goat

Expression System: E. coli

IFN-beta Protein, Chicken, Recombinant (His)

Cat.No: TMPH-00374

Species: Chicken

Expression System: E. coli

IFN-omega Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00833

Species: Human

Expression System: HEK293 Cells

IFN gamma Protein, Marmota monax, Recombinant (His)

Cat.No: TMPH-02451

Species: Marmota monax

Expression System: P. pastoris (Yeast)

IFN gamma Protein, Guinea Pig, Recombinant (His)

Cat.No: TMPH-00778

Species: Guinea pig

Expression System: E. coli

IFN-omega Protein, Bovine, Recombinant (His & SUMO)

Cat.No: TMPH-00277

Species: Bovine

Expression System: E. coli

IFN-alpha 13/IFNA13 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-02347

Species: Mouse

Expression System: HEK293 Cells

IFN gamma Protein, Sheep, Recombinant (E. coli, His)

Cat.No: TMPH-03494

Species: Sheep

Expression System: E. coli

IFN-alpha 2/IFNA2 Protein, Mouse, Recombinant

Cat.No: TMPJ-00747

Species: Mouse

Expression System: E. coli

IFN-alpha 1/IFNA1 Protein, Human, Recombinant (hFc)

Cat.No: TMPK-00075

Species: Human

Expression System: HEK293 Cells

IFN-alpha 13/IFNA13 Protein, Cynomolgus, Recombinant (hFc)

Cat.No: TMPY-03320

Species: Cynomolgus

Expression System: HEK293 Cells

IFN-alpha 13/IFNA13 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPY-03375

Species: Cynomolgus

Expression System: HEK293 Cells

IFN-alpha 1/IFNA1 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPK-00074

Species: Mouse

Expression System: HEK293 Cells

IFN-alpha 6/IFNA6 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00780

Species: Human

Expression System: HEK293 Cells

IFN-alpha 13/IFNA13 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-03891

Species: Mouse

Expression System: HEK293 Cells

IL-18 Protein (Primary Amine Labeling), Human, Recombinant, Biotinylated

Cat.No: TMPK-00076

Species: Human

Expression System: E. coli

IL-18R alpha Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00317

Species: Human

Expression System: HEK293 Cells

IL-18R alpha Protein, Cynomolgus, Recombinant (aa 22-329, His)

Cat.No: TMPK-00512

Species: Cynomolgus

Expression System: HEK293 Cells

IL-18R alpha Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00316

Species: Human

Expression System: HEK293 Cells

CXCL10 Protein, Human, Recombinant (hFc & His)

Cat.No: TMPJ-00008

Species: Human

Expression System: HEK293 Cells

BAFF/TNFSF13B Protein, Human, Recombinant (Avi & hFc), Biotinylated

Cat.No: TMPJ-00177

Species: Human

Expression System: HEK293 Cells

SLAMF6 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPJ-00218

Species: Human

Expression System: HEK293 Cells

PD-1 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPJ-00181

Species: Human

Expression System: HEK293 Cells

IL-21R Protein, Mouse, Recombinant (aa 20-236, His)

Cat.No: TMPJ-01337

Species: Mouse

Expression System: HEK293 Cells

我们的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved. 沪ICP备20019793号-4

沪公网安备 31010602006700号

沪公网安备 31010602006700号

TargetMol Loading

联系我们

电话：

400-820-0310

邮箱：

service@tsbiochem.com

QQ：

2881945090（终端用户）

2885109491（经销商）

经销：

终端：

地址：

上海市静安区江场三路238号8楼